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VARIOUS ENDOCRINE glands and endocrine products have been found to have an influence on the process of hemopoiesis. Hypophysectomy induces a profound anemia in the dog (Aschner, 1912), in the rabbit (Houssay, Royer, and Orias, 1931), and in the rat (Stewart, Greep, and Meyer, 1935; Meyer, Stewart, Thewlis, and Rusch, 1937; Vollmer, Gordon, Levenstein, and Charipper, 1939; Crafts, 1941). In addition, many clinical reports support the theory that the pituitary gland is concerned in some manner as a regulator of erythropoiesis. Castration has been reported as a cause of anemia in the male rabbit (Ferrari, 1930), the male rat (Steinglass, Gordon, and Charipper, 1941), in fowl (Arvy, 1942-43), in the hampster (Stein and Jacobsen, 1944), and in the human (McCullagh and Jones, 1942).
Roger Crafts (Sun,) studied this question.