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Abstract An environmentally benign four-component reaction in aqueous medium in the presence of cetyltrimethylammonium chloride (CTACl) has been developed for the synthesis of 6-amino-3-methyl-4-aryl-/1-phenyl-1,4-dihydropyrano2,3-cpyrazole-5-carbonitrile. The method presented is mild, environmentally friendly, inexpensive, and functionality tolerant and gives the products in good to excellent yields.
Wu et al. (Fri,) studied this question.