Supervisor support was inversely associated with IL-6 levels (β = -0.24, p < 0.01), suggesting a potential mechanism for beneficial cardiovascular effects in working men.
Cross-Sectional (n=137)
Does source-specific social support improve circulating inflammatory markers in male white-collar employees?
Social support from immediate supervisors is associated with lower levels of the inflammatory marker IL-6 in male white-collar workers, suggesting a potential mechanism for cardiovascular benefit.
Effect estimate: β = -0.24
p-value: p=< 0.01
BACKGROUND: Despite known beneficial effects of social support on cardiovascular health, the pathway through which sources of support (supervisor, coworkers, family/friends) influence inflammatory markers is not completely understood. PURPOSE: We investigated the independent and moderating associations between social support and inflammatory markers. METHODS: A total of 137 male white-collar employees underwent a blood draw for measurement of high-sensitive C-reactive protein (hs-CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), monocyte and leukocyte counts, and completed a questionnaire on social support. RESULTS: Multivariable linear regression analyses controlling for covariates revealed that supervisor support was inversely associated with IL-6 (β = -0.24, p < 0.01) while coworker support was marginally associated with TNF-α (β = -0.16, p < 0.10). Support from family/friends was not associated with inflammatory markers. CONCLUSION: Social support from the immediate supervisor may be a potential mechanism through which social support exerts beneficial effects on inflammatory markers in working men.
Nakata et al. (Tue,) reported a cross-sectional. Social support (supervisor, coworkers, family/friends) was evaluated on Circulating inflammatory markers (hs-CRP, IL-6, TNF-α, monocyte and leukocyte counts) (β = -0.24, p=< 0.01). Supervisor support was inversely associated with IL-6 levels (β = -0.24, p < 0.01), suggesting a potential mechanism for beneficial cardiovascular effects in working men.
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