Recent Advances in Hemophilia Care

This compact monograph reflects the current art and knowledge of hemophilia from a symposium in April 1989. By using a typed manuscript format, rapid publication was possible. Problems are organized in six major groups: genetics, inhibitor management, complications of hemophilia treatment, clotting factor concentrates, orthopedic care, and von Willebrand's disease. Each of the major sections includes contributions from leaders in their respective fields. Bibliographies contain both the classic studies and the most recent contributions. In the section on the management of inhibitors, all of the various strategies are nicely reviewed. Treatment had been frustrating to physicians and not very satisfactory for patients until the recent advent of porcine concentrates and immune tolerance induction regimens. The tragedy of human immunodeficiency virus and hepatitis is all too clear. Prior to the disaster of the acquired immunodeficiency syndrome, chronic end-stage liver disease was the number two cause of death (after hemorrhage) in patients