Aortic valve replacement with the Freestyle bioprosthesis provided 82.3% freedom from reoperation for structural valve deterioration at 15 years, with better outcomes in patients ≥60 years.
Cohort (n=430)
BACKGROUND: Stentless aortic bioprostheses were designed to provide enhanced hemodynamic performance and potentially greater longevity. The present report describes the outcomes of patients with the Freestyle stentless bioprosthesis followed for ≤18 years. METHODS AND RESULTS: Between 1993 and 2011, 430 patients underwent primary aortic valve replacement with a Freestyle bioprosthesis in the subcoronary position. Mean age was 68.2 ± 8.2 years. All of the clinical and echocardiographic data were collected prospectively. Mean overall follow-up was 9.1 ± 4.4 years and was complete in all of the patients. In-hospital mortality was 3.5% (n=15). Overall, 10- and 15-year survival were 60.7% and 35.0%, respectively. Fifty-one patients required reoperation during follow-up, including 27 for structural valve deterioration (SVD). Overall, freedom from reoperation was 91.0% and 75.0% at 10 and 15 years, whereas freedom from reoperation for SVD was 95.9% and 82.3%, respectively. At 10 and 15 years, freedom from reoperation for SVD was 94.0% and 62.6% for patients 60 years of age. Severe aortic insufficiency with leaflet tear is the major mode of SVD leading to reoperation in these patients.
Mohammadi et al. (Mon,) conducted a cohort in Aortic valve disease requiring replacement (n=430). Freestyle stentless aortic bioprosthesis was evaluated on Freedom from reoperation for structural valve deterioration (SVD) at 15 years. Aortic valve replacement with the Freestyle bioprosthesis provided 82.3% freedom from reoperation for structural valve deterioration at 15 years, with better outcomes in patients ≥60 years.