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In 1935, Greenfield and Carmichael made a quantitative study of the fibre content of the anterior tibial nerve of the foot in patients suffering from subacute combined degeneration of the spinal cord and from alcoholic polyneuritis. Some nerves from healthy subjects were also examined. Subsequently it was suggested by from which we can estimate exactly the amount of loss of myelinated fibres'. However, Garven, Gairns, and Smith (1962) have questioned the reliability of the anterior tibial nerve for quantita- tive study, and have drawn attention to the variability of its fibre content in normal people. The present work was designed to investigate these conflicting views and to demonstrate the extent and nature of such variability.
M Swallow (Wed,) studied this question.
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