Selective baroreflex failure with preserved parasympathetic control of heart rate can manifest as episodes of severe bradycardia and asystole.
Case Report (n=1)
Highlights a rare presentation of selective baroreflex failure with preserved parasympathetic control leading to malignant vagotonia, requiring unique therapeutic strategies.
Baroreflex failure is characterized by dramatic fluctuations of sympathetic activity and paroxysms of hypertension and tachycardia. In contrast, unopposed parasympathetic activity has not been described in patients with baroreflex failure because of concurrent parasympathetic denervation of the heart. We describe the unusual case of a patient with baroreflex failure in a setting of preserved parasympathetic control of HR manifesting episodes of severe bradycardia and asystole. Thus, parasympathetic control of the HR may be intact in occasional patients with baroreflex failure. Patients with this selective baroreflex failure require a unique therapeutic strategy for the control of disease manifestations.
Jordan et al. (Sat,) conducted a case report in Selective baroreflex failure (n=1). Selective baroreflex failure was evaluated on Episodes of severe bradycardia and asystole. Selective baroreflex failure with preserved parasympathetic control of heart rate can manifest as episodes of severe bradycardia and asystole.