Key points are not available for this paper at this time.
n this issue of Circulation, Pischon and colleagues 1 present provocative data pitting the power of non-highdensity lipoprotein cholesterol (non-HDL-C) versus apolipoprotein (apo) B to predict coronary heart disease (CHD) development in healthy men.They conclude not only that apoB is a superior predictor of CHD risk but, in addition, that "the practical application of our findings would be the substitution of apoB for LDL-C and non-HDL-C for screening and treatment of CHD risk.
Margo A. Denke (2005) studied this question.