A simple three-coefficient exponential constitutive law accurately predicted the stress-stretch behavior of cardiac mitral valve leaflets over a wide range of deformations.
A newly formulated three-coefficient exponential constitutive law accurately predicts the mechanical stress-stretch behavior of mitral valve tissue, which could aid in bioprosthetic development and mechanical modeling.
Biaxial mechanical testing and theoretical continuum mechanics analysis are employed to formulate a constitutive law for cardiac mitral valve anterior and posterior leaflets. A strain energy description is formulated based on the fibrous architecture of the tissue, accurately describing the large deformation, highly nonlinear transversely isotropic material behavior. The results show that a simple three-coefficient exponential constitutive law provides an accurate prediction of stress-stretch behavior over a wide range of deformations. Regional heterogenity may be accommodated by spatially varying a single coefficient and incorporating collagen fiber angle. The application of this quantitative information to mechanical models and bioprosthetic development could provide substantial improvement in the evaluation and treatment of valvular disease, surgery, and replacement.
May‐Newman et al. (Sun,) conducted a other in Mitral valve tissue mechanics. Biaxial mechanical testing and continuum mechanics analysis was evaluated on Stress-stretch behavior prediction. A simple three-coefficient exponential constitutive law accurately predicted the stress-stretch behavior of cardiac mitral valve leaflets over a wide range of deformations.
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