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We identified three factors influencing the onset of SPMS in untreated patients with RRMS: motor onset symptoms and male gender were associated with both a shorter time to and a younger age at SPMS. A younger age at disease onset should not be viewed as indicating a better prognosis.
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Marcus Koch
Elaine Kingwell
Peter Rieckmann
Journal of Neurology Neurosurgery & Psychiatry
Columbia University
University of British Columbia
University Medical Center Groningen
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Koch et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69d9479726e251a0196840cf — DOI: https://doi.org/10.1136/jnnp.2010.208173
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