Percutaneous pulmonary valve implantation significantly reduced right ventricular systolic pressure from 63 to 45 mm Hg (P<0.001) and right ventricular outflow tract gradient.
Cohort (n=155)
Absolute Event Rate: 45% vs 63%
p-value: p=<0.001
BACKGROUND: Percutaneous pulmonary valve implantation was introduced in the year 2000 as a nonsurgical treatment for patients with right ventricular outflow tract dysfunction. METHODS AND RESULTS: Between September 2000 and February 2007, 155 patients with stenosis and/or regurgitation underwent percutaneous pulmonary valve implantation. This led to significant reduction in right ventricular systolic pressure (from 63+/-18 to 45+/-13 mm Hg, P25 mm Hg (log-rank test P=0.01) were associated with a higher risk of reoperations. CONCLUSIONS: Percutaneous pulmonary valve implantation resulted in the ability to avoid surgical right ventricular outflow tract revision in the majority of cases. This procedure might reduce the number of operations needed over the total lifetime of patients with right ventricle-to-pulmonary artery conduits.
Lurz et al. (Mon,) conducted a cohort in Right ventricular outflow tract dysfunction (n=155). Percutaneous pulmonary valve implantation was evaluated on Right ventricular systolic pressure (mm Hg) (p=<0.001). Percutaneous pulmonary valve implantation significantly reduced right ventricular systolic pressure from 63 to 45 mm Hg (P<0.001) and right ventricular outflow tract gradient.