Endothelium-derived neuregulin protects cardiac myocytes against ischemic injury, highlighting its signaling pathway as a potential therapeutic target.
Together, these data demonstrate that EC-derived NRG plays an important role in cardiac myocyte protection against ischemic injury in the heart and supports the idea that manipulation of this signaling pathway may be an important clinical target in this setting.
Hedhli et al. (Tue,) studied this question.
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