June 1, 1978
View Full PaperSelective Purification of a Single Population of Glucocorticoid Receptors From Rat Brain
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Abstract
Abstract— A 200‐fold purification of glucocorticoid receptors from rat brain was achieved with 21% recovery using affinity chromatography via deoxycorticosterone hemisuccinate covalently coupled to BSA‐Sepharose 4B. Subsequent chromatography of the affinity column eluate via a DE‐52 anionexchanger revealed that this purification concerned selectively one of the two glucocorticoid receptor systems in rat brain.