Three Families with Familial Cardiomyopathy

Article1 September 1965Three Families with Familial CardiomyopathyDANIEL L. BOYD, M.D., MARVIN E. MISHKIN, M.D., HARVEY FEIGENBAUM, M.D., PASQUALE D. GENOVESE, M.D., F.A.C.P.DANIEL L. BOYD, M.D.Search for more papers by this author, MARVIN E. MISHKIN, M.D.Search for more papers by this author, HARVEY FEIGENBAUM, M.D.Search for more papers by this author, PASQUALE D. GENOVESE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-3-386 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1949 Evans (1) described a degenerative disease of the myocardium that occurred in the same family and named the condition "familial cardiomegaly." Since that original report, Battersby and Glenner (2) have reported a family in which five members were affected with a similar myocardial disease, and the authors used the term "familial cardiomyopathy" to describe the entity more accurately. Numerous other reports have been published (3-9), including a review of the literature by Beasley (10).The etiology of this form of heart disease is unknown, but evidence for a genetic factor increases as more reports are published. The clinical...References1. EVANS W: Familial cardiomegaly. Brit. Heart J. 11: 68, 1949. CrossrefMedlineGoogle Scholar2. BATTERSBYGLENNER EJGG: Familial cardiomyopathy. Amer. J. Med. 30: 382, 1961. CrossrefMedlineGoogle Scholar3. GARRETTHAYRICKARDS GWJAG: Familial cardiomegaly. J. Clin. Path. 12: 355, 1959. CrossrefMedlineGoogle Scholar4. HOLLMANGOODWINTEARERENWICK AJFDJW: A family with obstructive cardiomyopathy (asymmetrical hypertrophy). Brit. Heart J. 22: 449, 1960. CrossrefMedlineGoogle Scholar5. PARÉFRASERPIROZYNSKISHANKSSTUBBINGTON JARGWJJAD: Hereditary cardiovascular dysplasia. Amer. J. Med. 31: 37, 1961. CrossrefMedlineGoogle Scholar6. BISHOPCAMPBELLJONES JMMEW: Cardiomyopathy in four members of a family. Brit. Heart J. 24: 715, 1962. CrossrefMedlineGoogle Scholar7. BARRYHALL MM: Familial cardiomyopathy. Ibid., p. 613. Google Scholar8. WHITFIELD AG: Familial cardiomyopathy. Quart. J. Med. 30: 119, 1961. MedlineGoogle Scholar9. BRIGDEN W: Uncommon myocardial disease: the non-coronary cardiomyopathies. Lancet 2: 1243, 1957. CrossrefGoogle Scholar10. BEASLEY OC: Familial myocardial disease. Amer. J. Med. 29: 476, 1960. CrossrefMedlineGoogle Scholar11. STANBURY JB: Familial goiter, in The Metabolic Basis of Inherited Disease, edited by STANBURY, J. B., WYNGAARDEN, J. B., FREDRICKSON, D. S. McGraw-Hill Book Co., New York, 1960, p. 273. Google Scholar12. DUNCANBEST CHMM: Thyroxine-like compounds and cholesterol metabolism: differences in the effects of thyroxine, triiodothyronine and their formic add analogues. Endocrinology 63: 169, 1958. CrossrefMedlineGoogle Scholar13. WINTERSSOLOFF WLLA: Observations on sodium d-thyroxine as a hypocholesterolemic agent in persons with hypercholesterolemia with and without ischemic heart disease. Amer. J. Med. Sci. 243: 458, 1962. CrossrefMedlineGoogle Scholar14. BAROODYBAROODY NBWG: Effect of d-triiodothyronine on hypercholesterolemic subjects. Ibid., p. 338. Google Scholar15. TEARE D: Asymmetrical hypertrophy of the heart in young adults. Brit. Heart J. 20: 1, 1958. CrossrefMedlineGoogle Scholar16. DYEGENOVESEDALYBEHNKE CLPDWJRH: Primary myocardial disease. Part II. Hemodynamic alterations. Ann. Intern. Med. 58: 442, 1963. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, IndianaFrom the Medical Service, Veterans Administration Hospital, and the Department of Medicine, Indiana University School of Medicine, Indianapolis, Ind.Supported by grant H6308, Heart Research Center, National Heart Institute, U. S. Public Health Service, Bethesda, Md., and the Indiana Heart Association, Indianapolis, Ind.This work was completed during the tenure of Drs. Boyd and Mishkin as Indiana Heart Association Student Cardiovascular Research Fellows.Requests for reprints should be addressed to Pasquale D. Genovese, M.D., Chief, Cardiology Section, Veterans Administration Hospital, 1481 W. 10th St., Indianapolis, Ind. 46207. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHarvey Feigenbaum, MD, and the Creation of Clinical Echocardiography: A Conversation With Barry J. Maron, MDX-Linked Dilated CardiomyopathyThe Lown-Ganong-Levine SyndromeClinical pathologic conferenceFamiliäre KardiomegalieUncommon or commonly unrecognized causes of heart failureQUÉBEC BEER-DRINKERS’CARDIOMYOPATHY: CLINICAL AND HEMODYNAMIC ASPECTS*ON THE POSSIBILITY THAT A TYPE OF HUMAN MUSCULAR DYSTROPHY COMMENCES IN MYOCARDIUM*ENDOMYOCARDIAL FIBROELASTOSIS IN AN ADULT EUROPEAN 1 September 1965Volume 63, Issue 3Page: 386-401KeywordsCardiomyopathiesEtiologyGenetic diseasesGeneticsHeartHospital medicineMedical servicesMyocardiumResearch grantsThyroid Issue Published: 1 September 1965 PDF DownloadLoading ...