Chromophobe Cell Renal Carcinoma: Clinicopathological Features of 50 Cases

No AccessJournal of UrologyClinical Urology: Original Article1 Sep 1995Chromophobe Cell Renal Carcinoma: Clinicopathological Features of 50 Cases Thomas B. Crotty, George M. Farrow, and Michael M. Lieber Thomas B. CrottyThomas B. Crotty , George M. FarrowGeorge M. Farrow , and Michael M. LieberMichael M. Lieber View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66944-1AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We review the clinicopathological features of chromophobe cell renal carcinoma. Materials and Methods: Cases were identified by reviewing the histology of all renal neoplasms resected between 1977 and 1990. Clinical data were obtained by chart review. Results: Of 50 cases a majority (53 percent) were discovered incidentally and most (86 percent) were stage I. Typical pathological findings included the presence of 2 cell types (pale and eosinophilic), reactivity for Hale's colloidal iron, ultrastructural cytoplasmic vesicles and deoxyribonucleic acid aneuploidy. At last followup 47 patients (94 percent) were tumor-free or dead of unrelated causes. Survival was similar in patients with clear cell carcinoma of similar grade and stage. Conclusions: Chromophobe cell carcinoma is a morphologically distinctive neoplasm with a favorable prognosis. Distinction from renal oncocytoma is important. References 1 : Human chromophobe cell renal carcinoma. Virchows Arch. B1985; 48: 207. Google Scholar 2 : Chromophobe cell renal carcinoma and its variants—a report on 32 cases. J. Path.1988; 155: 277. Google Scholar 3 : Diseases of the kidney.. In: Urological Pathology. Edited by . Philadelphia: W. B. Saunders Co.1989: 409. chapt. 8. Google Scholar 4 : Chromophobe cell carcinoma: analysis of five cases. Amer. J. Surg. Path.1990; 14: 260. 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Link, Google Scholar Division of Anatomic Pathology and Department of Urology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited bySHEIR K, EL-AZAB M, MOSBAH A, EL-BAZ M and SHAABAN A (2018) DIFFERENTIATION OF RENAL CELL CARCINOMA SUBTYPES BY MULTISLICE COMPUTERIZED TOMOGRAPHYJournal of Urology, VOL. 174, NO. 2, (451-455), Online publication date: 1-Aug-2005.ISLAM A, EHARA T, KATO H, HAYAMA M, KOBAYASHI S, IGAWA Y and NISHIZAWA O (2018) Calponin h1 Expression in Renal Tumor Vessels: Correlations With Multiple Pathological Factors of Renal Cell CarcinomaJournal of Urology, VOL. 171, NO. 3, (1319-1323), Online publication date: 1-Mar-2004.MÉJEAN A, OUDARD S and THIOUNN N (2018) Prognostic Factors of Renal Cell CarcinomaJournal of Urology, VOL. 169, NO. 3, (821-827), Online publication date: 1-Mar-2003.PANTUCK A, ZISMAN A and BELLDEGRUN A (2018) THE CHANGING NATURAL HISTORY OF RENAL CELL CARCINOMAJournal of Urology, VOL. 166, NO. 5, (1611-1623), Online publication date: 1-Nov-2001.LEE C, KATZ J, SHI W, THALER H, REUTER V and RUSSO P (2018) SURGICAL MANAGEMENT OF RENAL TUMORS 4 CM. OR LESS IN A CONTEMPORARY COHORTJournal of Urology, VOL. 163, NO. 3, (730-736), Online publication date: 1-Mar-2000.ZAMBRANO N, LUBENSKY I, MERINO M, LINEHAN W and WALTHER M (2018) HISTOPATHOLOGY AND MOLECULAR GENETICS OF RENAL TUMORS: TOWARD UNIFICATION OF A CLASSIFICATION SYSTEMJournal of Urology, VOL. 162, NO. 4, (1246-1258), Online publication date: 1-Oct-1999.DECHET C, BOSTWICK D, BLUTE M, BRYANT S and ZINCKE H (2018) RENAL ONCOCYTOMA: MULTIFOCALITY, BILATERALISM, METACHRONOUS TUMOR DEVELOPMENT AND COEXISTENT RENAL CELL CARCINOMAJournal of Urology, VOL. 162, NO. 1, (40-42), Online publication date: 1-Jul-1999.Kinoshita H, Ogawa O, Mitsumori K, Kakehi Y, Terachi T and Yoshida O (2018) LOW FREQUENCY OF POSITIVE TELOMERASE ACTIVITY IN A CHROMOPHOBE SUBTYPE OF RENAL CELL CARCINOMAJournal of Urology, VOL. 159, NO. 1, (245-251), Online publication date: 1-Jan-1998. Volume 154Issue 3September 1995Page: 964-967 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.Metrics Author Information Thomas B. Crotty More articles by this author George M. Farrow More articles by this author Michael M. Lieber More articles by this author Expand All Advertisement PDF downloadLoading ...