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In previous articles1the symptoms characteristic for gonadal afunction and hypofunction in both the human female and the male have been outlined and described. That man is subject to varying degrees of sexual function and does have a climacteric is now an established fact. GENERAL DESCRIPTION OF THE SYNDROME The symptoms of this syndrome may be present in any one of several conditions which can occur in man, such as eunuchism, cryptorchism, hypogonadism, castration and the climacteric. Eunuchism results from complete absence of testicular function in man and the absence of function must be present in the person before and at the time for the occurrence of secondary sexual development. If there is some testicular function at the time of puberty and a degree of secondary sexual development occurs, then the condition must be classified as hypogonadism. Eunuchism may be due to congenital absence of the testicles (a condition
AUGUST A. WERNER (Sat,) studied this question.