Coronary artery disease was present in 10.1% of women compared to 49.6% of men referred for cardiovascular diagnosis, with most female cases associated with hypertension or diabetes.
Observational (n=3,807)
No
Coronary artery disease is significantly less common in women than men in a cardiovascular referral practice, and in women, it is highly associated with hypertension and diabetes.
Effect estimate: 4.9 times higher in men
Absolute Event Rate: 10.1% vs 49.6%
In women, especially those under the age of 50, coronary artery disease is unusual in the absence of diabetes or hypertension. Yet precordial pain simulating angina pectoris is a very common symptom. Although experienced clinicians have been aware of this fact for years, it is overlooked again and again in daily practice and many mistaken diagnoses result. During the past seven years in an office practice representing largely patients referred for cardiovascular diagnosis, we have seen 1,672 women, of whom 169, or 10.1 per cent, had coronary artery disease. In the same period we saw 2,135 men, of whom 1,059, or 49.6 per cent, had coronary artery disease. The frequency is 4.9 times as great in men as in women. Of the 169 cases in women, 125, or 74 per cent, were associated with hypertension alone, twenty-five,or 14.8 per cent, with both diabetes and hypertension, and six, or 3.5 per
Hyman Levy (Sat,) conducted a observational in Coronary artery disease (n=3,807). Coronary artery disease was present in 10.1% of women compared to 49.6% of men referred for cardiovascular diagnosis, with most female cases associated with hypertension or diabetes.
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