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When the fall in left ventricular pressure during isovolumic relaxation is treated as a monoexponential the rate of relaxation can be measured by a time constant. Though an empirical measurement, the time constant has been used extensively to study relaxation. It can be accepted, however, as a valid measurement only if isovolumic pressure fall approximates very closely to a monoexponential in a wide range of circumstances.
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D S Thompson
St. Paul's Hospital
C B Waldron
Memorial Health University Medical Center
D J Coltart
Guy's and St Thomas' NHS Foundation Trust
Heart
St Thomas' Hospital
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Thompson et al. (Tue,) studied this question.
synapsesocial.com/papers/6a1d0252cc9f7df1b704bd8e — DOI: https://doi.org/10.1136/hrt.49.3.250
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