July 23, 2011Open Access
View Full PaperA quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia
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Abstract
Strong associations between premorbid IQ and risk for schizophrenia, and age of illness onset argue for a widespread neurodevelopmental contribution to schizophrenia that operates across the entire range of intellectual ability. This also suggests higher IQ may be protective in schizophrenia, perhaps by increasing active cognitive reserve.