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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrostatic Basis for Enzyme CatalysisArieh Warshel, Pankaz K. Sharma, Mitsunori Kato, Yun Xiang, Hanbin Liu, and Mats H. M. OlssonView Author Information Department of Chemistry, University of Southern California, SGM Building 418, 3620 McClintock Avenue, Los Angeles, California 90089-1062 Cite this: Chem. Rev. 2006, 106, 8, 3210–3235Publication Date (Web):June 15, 2006Publication History Received7 November 2005Published online15 June 2006Published inissue 1 August 2006https://pubs.acs.org/doi/10.1021/cr0503106https://doi.org/10.1021/cr0503106research-articleACS PublicationsCopyright © 2006 American Chemical SocietyRequest reuse permissionsArticle Views13626Altmetric-Citations1088LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Catalysis,Chemical reactions,Electrostatics,Free energy,Peptides and proteins Get e-Alerts
Warshel et al. (Thu,) studied this question.