Gender, Coronary Artery Disease, and Coronary Bypass Surgery

Editorials15 April 1990Gender, Coronary Artery Disease, and Coronary Bypass SurgeryNanette K. Wenger, MDNanette K. Wenger, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-8-557 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe Framingham Heart Study (1) provided 30 years of observational data that emphasize striking differences in the clinical presentation of and prognosis for coronary heart disease according to gender. Coronary artery disease occurred consistently at a later age among women than men; the mean age at initial clinical manifestation was 10 years older for women than for men, and that for myocardial infarction 20 years older. The reasons for this phenomenon remain largely unexplained.Angina pectoris was highlighted as the predominant initial clinical presentation of coronary heart disease among women, occurring in 56% of women compared with 43% of men....References1. LernerKannel DW. Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population. Am Heart J. 1986;111:383-90. CrossrefMedlineGoogle Scholar2. KannelAbbott WR. Incidence and prognosis of myocardial infarction in women: The Framingham Study. In: Eaker ED, Packard B, Wenger NK, et al., eds. Coronary Heart Disease in Women. New York: Haymarket Doyma; 1987:208-14. Google Scholar3. KannelSorlieMcNamara WPP. Prognosis after initial myocardial infarction: The Framingham Study. Am J Cardiol. 1979;44:53-9. CrossrefMedlineGoogle Scholar4. TollerStoneMuller GPJ. Effects of gender and race on prognosis after myocardial infarction: adverse prognosis for women, particularly black women. 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CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Nanette K. 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