Is the measurement of coronary blood flow from the rate of myocardial nitrous oxide desaturation valid and efficient compared to the saturation technique in dogs and man?
The nitrous oxide desaturation technique is a valid and time-saving method for measuring coronary blood flow in dogs and humans.
A technic of measuring left ventricular coronary blood flow in dogs and man from the rate of desaturation of nitrous oxide from the myocardium is presented. The desaturation technic appears valid in comparison with the previously described saturation technic, and affords definite technical advantages. By combining the two technics, flows may be measured within much less timethan by repeating either method alone.
Goodale et al. (Sun,) studied this question.