Percutaneous closure using Amplatzer septal occluders was feasible in 79.5% of patients with isolated secundum-type atrial septal defects, while 20.5% required surgical closure.
Observational (n=190)
Does percutaneous closure using Amplatzer septal occluders allow successful treatment of isolated secundum-type atrial septal defects in patients with morphological variations?
Percutaneous closure using Amplatzer septal occluders is feasible for a variety of secundum-type ASD morphologies, including those with deficient rims, multiple defects, and perforated aneurysms.
Absolute Event Rate: 79.5% vs 20.5%
The aim of the study was to assess the morphology of secundum-type atrial septal defects (ASD) with a view to percutaneous closure using Amplatzer septal occluders (ASO). One hundred and ninety patients who underwent closure of isolated secundum-type ASD between September 1995 and January 2000 were included. The morphology of the defects was studied using transthoracic and transesophageal echocardiography. Patients with defects of suitable morphology and size underwent percutaneous closure using ASO. The remaining patients underwent surgical closure. Centrally placed defects were observed in 46 patients (24.2%). Morphological variations of secundum-type ASD were detected in 144 patients (75.8%). One hundred and fifty-one patients (79.5%) underwent percutaneous closure using ASO. Thirty-nine patients (20.5%) underwent surgical closure. Centrally placed defects, defects with deficient superior anterior rim, multiple defects, and perforated aneurysms of the interatrial septum are morphological variations of secundum-type ASD suitable for percutaneous closure using ASO. Cathet Cardiovasc Intervent 2001;53:386-391.
Podnar et al. (Fri,) conducted a observational in Secundum-type atrial septal defects (n=190). Percutaneous closure using Amplatzer septal occluders vs. Surgical closure was evaluated on Feasibility of percutaneous closure based on defect morphology. Percutaneous closure using Amplatzer septal occluders was feasible in 79.5% of patients with isolated secundum-type atrial septal defects, while 20.5% required surgical closure.