Pulse Journal Club Trending Explore Questions Researchers

Download the App

Join discussions, follow papers, and never miss your next session.

© Synapse Social LLC, 2026Privacy Policy

Home Explore Journal Club Trending

⌘+K

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses | Synapse

December 21, 1998Open Access

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

Key Points

Key points are not available for this paper at this time.

Abstract

For many viral infections, resolution of illness is associated with long-term host control of viremia rather than viral eradication. An example is EBV infection, and the fact that host immune suppression is associated with EBV-induced disease suggests that it is the immune system that is holding the

Mark Helpful

Bookmark

Relay

View Full Paper

Mark Helpful

Bookmark

Relay

View Full Paper

Cite This Study

Kalams et al. (Mon,) studied this question.

synapsesocial.com/papers/6a16156854ab0a6a51195b6d https://doi.org/https://doi.org/10.1084/jem.188.12.2199

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function1998 · 1,966 citations
2Serial triggering of many T-cell receptors by a few peptide–MHC complexes1995 · 1,130 citations
3Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV1993 · 289 citations
4T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions1998 · 2,610 citations
5Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease.1993 · 422 citations