September 1, 2000Open Access
View Full PaperPrevalence of Coronary Artery Disease, Ischemic Stroke, and Symptomatic Peripheral Arterial Disease and of Associated Risk Factors in Older Men and Women With and Without Diabetes Mellitus
Key Result
Older adults with diabetes mellitus had a significantly higher prevalence of coronary artery disease, ischemic stroke, and symptomatic peripheral arterial disease than those without (p<0.0001).
Study Design
Type
Cross-Sectional (n=1,911)
Multicenter
No
PICO
P
Population
1,911 older men and women seen in an academic outpatient geriatrics practice, evaluated for the prevalence of cardiovascular diseases and risk factors by diabetes status.
E
Exposure / Comparator
Diabetes mellitus vs Without diabetes mellitus
O
Primary Outcome
Prevalence of coronary artery disease, ischemic stroke, and symptomatic peripheral arterial disease, p=<0.0001
Main Result
p-value: p=<0.0001
Abstract
The authors performed a retrospective analysis of the prevalence of coronary artery disease, ischemic stroke, and symptomatic peripheral arterial disease and of associated risk factors in 99 men (mean age 79±8 years) with diabetes mellitus vs. 368 men (mean age 81±8 years) without diabetes mellitus, and in 260 women (mean age 80±8 years) with diabetes mellitus vs. 1184 women (mean age 81±8 years) without diabetes mellitus. All patients were seen in an academic outpatient geriatrics practice. Diabetic men had a higher prevalence of coronary artery disease, ischemic stroke, and symptomatic peripheral arterial disease (p<0.0001); a higher prevalence of smoking (p=0.023), hypertension (p<0.0001), and obesity (p=0.0007); higher levels of serum total and low density lipoprotein cholesterol (p<0.0001) and triglycerides (p=0.003); and lower levels of serum high density lipoprotein cholesterol (p=0.0001) than men without diabetes mellitus. Diabetic women had a higher prevalence of coronary artery disease, ischemic stroke, and symptomatic peripheral arterial disease (p<0.0001); a higher prevalence of hypertension and obesity (p<0.0001); higher levels of serum total and low density lipoprotein cholesterol (p=0.0001) and triglycerides (p=0.005); and lower levels of serum high density lipoprotein cholesterol (p=0.0001) than women without diabetes mellitus. (c) 2000 by CHF, Inc.