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The substantial prevalence of noncompliance with drugs in populations of patients with treated hypertension suggests that a reliable, clinically applicable screening test for this behavior is needed. Among employed white males, patient response to a nonjudgmental clinician inquiry has been reported to be highly predictive of noncompliance when positive but relatively insensitive (40 per cent). We assessed the performance of patient self-report in a demographically different population and confirmed the generalizability of prior observations. A compound decision rule combining blood pressure and verbal inquiry observations, however, had higher sensitivity (83 per cent) for noncompliance in our population than self-report alone (55 per cent) and could be considered for use when the prevalence of noncompliance among uncontrolled hypertensives is sufficiently high. Because 40 per cent of well-controlled hypertensives in our test population were noncompliant by pill-count, a question is raised regarding the need for "stepping down" drug therapy in some individuals under treatment for high blood pressure.
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Thomas S. Inui
University of North Carolina at Chapel Hill
William B. Carter
Defense Advanced Research Projects Agency
Roger E. Pecoraro
University of Washington
Medical Care
University of Washington
University of Washington Medical Center
Health Services Research & Development
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Inui et al. (Thu,) studied this question.
synapsesocial.com/papers/6a10df1663b25c787d9f9da4 — DOI: https://doi.org/10.1097/00005650-198110000-00008