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SINCE the time when radioactive iodine was first shown to be collected by thyroid tissue, the possibility of the collection of this radiationproducing substance by cancer of the thyroid has been under consideration (1). Investigation has subsequently been made on the uptake of radioactive iodine by various thyroidal tumors and particularly those carcinomas of the thyroid which have spread beyond the limits of complete surgical excision (1–28). This report concerns 119 patients with carcinoma of the thyroid who have been studied with radioactive iodine at the Thyroid Clinic of the Massachusetts General Hospital for the past six years. The purpose of this publication is to summarize some of the information that has been collected: 1) the uptake of radioactive iodine by carcinomas of the thyroid, 2) the means by which the uptake may be increased, 3) the therapeutic application in patients, and 4) the results of radiation not only in the malignant tissue but in other tissues of the body.
DOBYNS et al. (Thu,) studied this question.