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Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
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Derek M. Yellon
Derek J. Hausenloy
New England Journal of Medicine
University College London
University College Hospital
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Yellon et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d95d4a16f0d2beeba3c71a — DOI: https://doi.org/10.1056/nejmra071667