Breath-by-breath CPET systems demonstrated larger errors in oxygen uptake and carbon dioxide production and were less stable across different minute ventilation values than mixing chamber systems.
Cardiopulmonary exercise testing (CPET) has become an important diagnostic tool for patients with cardiorespiratory disease and can monitor athletic performance measuring maximal oxygen uptake Formula: see textVo2(; max). The aim of this study is to compare the accuracy and precision of a breath-by-breath and a mixing chamber CPET system, using two methods. First, this study developed a (theoretical) error analysis based on general error propagation theory. Second, calibration measurements using a metabolic simulator were performed. Error analysis shows that the error in oxygen uptake (Formula: see textVo2) and carbon dioxide production (Vco2Formula: see text) is smaller for mixing chamber than for breath-by-breath systems. In general, the error of the flow sensor Formula: see textδV, the error in temperature of expired air δT(B) and the delay time error δt(delay) are significant sources of error. Measurements using a metabolic simulator show that breath-by-breath systems are less stabile for different values of minute ventilation than mixing chamber systems.
Beijst et al. (Wed,) reported a other. Breath-by-breath CPET system vs. Mixing chamber CPET system was evaluated on Accuracy and precision of oxygen uptake and carbon dioxide production. Breath-by-breath CPET systems demonstrated larger errors in oxygen uptake and carbon dioxide production and were less stable across different minute ventilation values than mixing chamber systems.