Increased N-proBNP (HR 1.002; P<0.001) and decreased GFR (HR 0.972; P<0.005) were independent predictors of mortality in patients with chronic heart failure, whereas anemia was not.
Cohort (n=153)
No
Effect estimate: HR 1.002 (N-proBNP); HR 0.972 (GFR)
p-value: p=<0.001 (N-proBNP); <0.005 (GFR)
OBJECTIVES: The present study aimed to evaluate the prognostic value of B-type natriuretic peptide (N-proBNP), renal dysfunction and anemia in chronic heart failure (CHF) patients. METHODS: We analyzed data from a prospective cohort of 153 patients (mean age 64 years) with CHF referred to our hospital center. Clinical, echocardiographic and laboratory data were drawn during hospital recovery in all patients. Kidney dysfunction was defined as a glomerular filtration rate (GFR) or = 60 ml/min than in those with GFR < 60 ml/min (P < 0.001). CONCLUSION: Increased N-proBNP and decreased kidney function, but not anemia, are independent risk factors for mortality in patients with CHF.
Petretta et al. (Thu,) conducted a cohort in chronic heart failure (n=153). N-proBNP, renal dysfunction, and anemia was evaluated on mortality (HR 1.002 (N-proBNP); HR 0.972 (GFR), p=<0.001 (N-proBNP); <0.005 (GFR)). Increased N-proBNP (HR 1.002; P<0.001) and decreased GFR (HR 0.972; P<0.005) were independent predictors of mortality in patients with chronic heart failure, whereas anemia was not.