Device-guided breathing exercises did not significantly reduce office systolic blood pressure compared to listening to music (mean difference 4.7 mmHg) in hypertensive patients with type 2 diabetes.
RCT (n=30)
Single-blind
Sealed non-transparent envelopes
No
Does device-guided breathing exercise reduce blood pressure in hypertensive patients with type 2 diabetes mellitus?
Device-guided breathing exercises did not significantly reduce blood pressure compared to listening to music in hypertensive patients with type 2 diabetes, and many patients failed to achieve the target breathing rate.
Mean Difference: 4.7 (95% CI -11.7–2.3)
Absolute Event Rate: -7.5% vs -12.2%
p-value: p=0.86
OBJECTIVE: In patients with type 2 diabetes mellitus (DM2), it is hard to reach treatment objectives for blood pressure (BP) with classical treatment options. Recently, reducing breathing frequency has been advocated as a method to reduce BP. We examined if an electronic device such as Resperate, by reducing breathing frequency, would lead to BP reduction in a population of patients with DM2 and hypertension. Our secondary objective was to study the effect of this device on quality of life (QOL). METHODS: A randomized, single-blind, controlled trial was conducted over a period of 8 weeks to evaluate the effect of this therapy on BP and QOL. The control group listened to music and used no other therapeutic device. BP and QOL changes were studied in 30 patients with DM2 and hypertension. RESULTS: There was no significant difference in change in BP between groups; -7.5 95% confidence interval (CI) -12.7, -2.3/-1.0 (95% CI -5.5, 3.6) mmHg in the intervention group and -12.2 (95% CI -17.4, -7.0)/-5.5 (95% CI -9.7, -1.4) mmHg in the control group. Whether or not the target breathing frequency of 10 breaths/min was reached did not affect BP. There were no significant changes in QOL. CONCLUSIONS: The effects of Resperate on BP and QOL were not significantly different from those found in the control group. Furthermore, 40% of patients did not reach the target breathing frequency, making this device less suitable for clinical practice in patients with DM2.
Logtenberg et al. (Thu,) conducted a rct in Type 2 diabetes mellitus and hypertension (n=30). Device-guided breathing exercises (Resperate) vs. Listening to music (Discman) was evaluated on Change in office systolic blood pressure (MD 4.7, 95% CI -11.7 to 2.3, p=0.86). Device-guided breathing exercises did not significantly reduce office systolic blood pressure compared to listening to music (mean difference 4.7 mmHg) in hypertensive patients with type 2 diabetes.
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