Diabetics presenting to the emergency department with symptoms suggestive of acute myocardial infarction had a higher 1-year mortality rate than nondiabetics (25% vs 10%, p<0.001).
Cohort (n=7,157)
Does diabetes worsen the 1-year prognosis in patients presenting to the emergency department with symptoms suggestive of acute myocardial infarction?
Diabetic patients presenting to the emergency department with symptoms suggestive of AMI have a significantly higher 1-year mortality rate (25%) compared to non-diabetics (10%).
Absolute Event Rate: 25% vs 10%
p-value: p=<0.001
We evaluated the prognosis of 599 diabetics who came to the emergency department with chest pain or other symptoms suggestive of acute myocardial infarction (AMI). They made up 8% of the patients with such symptoms (n = 7,157). Diabetics had a 1-year mortality rate of 25% as compared with 10% for nondiabetics (p less than 0.001). The difference remained significant regardless of whether there was a strong or a vague initial suspicion of AMI. On admission, independent risk factors for death were age, acute congestive heart failure and initial degree of suspicion of AMI. We conclude that among diabetics who appear in the emergency department with chest pain or other symptoms suggestive of AMI, 25% are dead within 1 year. The prognosis is directly related to the initial suspicion of AMI.
Herlitz et al. (2008) conducted a cohort in Chest pain or symptoms suggestive of acute myocardial infarction (n=7,157). Diabetes vs. Nondiabetics was evaluated on 1-year mortality rate (p=<0.001). Diabetics presenting to the emergency department with symptoms suggestive of acute myocardial infarction had a higher 1-year mortality rate than nondiabetics (25% vs 10%, p<0.001).