What question did this study set out to answer?

The aim is to explore biomimetic total synthesis techniques for terpenes and steroids via polyolefin carbocyclizations.

November 30, 2005Open Access

A Case Study in Biomimetic Total Synthesis: Polyolefin Carbocyclizations to Terpenes and Steroids

Key Points

The aim is to explore biomimetic total synthesis techniques for terpenes and steroids via polyolefin carbocyclizations.
Analysis of polyolefin carbocyclization reactions
Investigation of reaction mechanisms and pathways
Synthesis of various terpenes and steroids through biomimetic approaches
Successful synthesis of key terpene and steroid structures using polyolefin methodologies.
Identification of new reaction pathways that mimic biological synthesis of these compounds.

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Case Study in Biomimetic Total Synthesis: Polyolefin Carbocyclizations to Terpenes and SteroidsRyan A. Yoder and Jeffrey N. JohnstonView Author Information Department of Chemistry, Indiana University, Bloomington, Indiana 47405-7102 Cite this: Chem. Rev. 2005, 105, 12, 4730–4756Publication Date (Web):November 30, 2005Publication History Received7 March 2005Published online30 November 2005Published inissue 1 December 2005https://pubs.acs.org/doi/10.1021/cr040623lhttps://doi.org/10.1021/cr040623lresearch-articleACS PublicationsCopyright © 2005 American Chemical SocietyRequest reuse permissionsArticle Views10224Altmetric-Citations425LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Biosynthesis,Cyclization,Hydrocarbons,Ions,Peptides and proteins Get e-Alerts

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