January 1, 2013Open Access

Chronic Kidney Disease Causes Disruption of Gastric and Small Intestinal Epithelial Tight Junction

NVNosratola D. VaziriUniversity of Geneva JYJun YuanUniversity of California, Riverside SNSohrab NazertehraniUniversity of California, Irvine

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Abstract

The present study extends the earlier finding of uremia-induced disruption of colonic epithelial TJ by documenting the involvement of the stomach, jejunum, and ileum as well.

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Vaziri et al. (Tue,) studied this question.

synapsesocial.com/papers/69d9ae955e5bcb4e3b8379fd https://doi.org/https://doi.org/10.1159/000353764

Also Consider

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1Oral Activated Charcoal Adsorbent (AST-120) Ameliorates Chronic Kidney Disease-Induced Intestinal Epithelial Barrier Disruption2013 · 101 citations
2Uremic Plasma Impairs Barrier Function and Depletes the Tight Junction Protein Constituents of Intestinal Epithelium2012 · 165 citations
3Role of Urea in Intestinal Barrier Dysfunction and Disruption of Epithelial Tight Junction in Chronic Kidney Disease2012 · 371 citations
4CKD impairs barrier function and alters microbial flora of the intestine2012 · 232 citations
5Disintegration of colonic epithelial tight junction in uremia: a likely cause of CKD-associated inflammation2011 · 307 citations

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