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October 16, 2012Seminars in Reproductive MedicineOpen Access

Obesity exacerbates the PCOS phenotype, especially cardiovascular risk factors such as glucose intolerance and dyslipidemia, and is associated with poor response to infertility treatment.

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Population

Women with obesity and polycystic ovary syndrome (PCOS)

Design

Review

Authors

RLRichard S. Legro

Discussion

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Overview

Supports weight management in obese PCOS; leaves open optimal interventions for fertility and CV outcomes.

Structured PICO

P
Population
Women with obesity and polycystic ovary syndrome (PCOS)
I
Intervention
Weight loss treatments (including bariatric surgery and lifestyle therapies)

Obesity exacerbates cardiovascular risk factors and infertility in PCOS, making weight loss a front-line therapy despite the need for further research on optimal treatments.

Limitations

  • Further studies are needed to identify the best treatments
  • The role of lifestyle therapies in women of normal weight with PCOS is uncertain

Cite This Study

Richard S. Legro (2012) studied this question.

synapsesocial.com/papers/6a01ca9a6668471b61d8ae47https://doi.org/10.1055/s-0032-1328878
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