Single-pill or fixed-dose combination therapy improves adherence and provides the antihypertensive efficacy needed to help patients achieve their blood pressure goals.
Does single-pill combination therapy improve adherence and blood pressure control in patients with elevated blood pressure?
Single-pill combination therapy is highlighted as an effective strategy to improve medication adherence and achieve blood pressure control in patients with hypertension.
Inadequate control of blood pressure may be attributed to both provider-related and patient-related factors. Health care provider-related factors may include an excessive reliance on monotherapy and reluctance to increase drug doses or add additional antihypertensive agents to the treatment regimen. The primary patient-related factor is nonadherence with the prescribed antihypertensive medication. Although the high cost of therapy is sometimes a reason for poor adherence, drug side effects or dosing considerations may be more important factors. Better adherence with antihypertensive medication is associated with a significantly greater likelihood of achieving blood pressure control and, consequently, with lower costs and reduced utilization of health care resources. Therefore, strategies that improve long-term adherence should be adopted. Single-pill, or fixed-dose, combination therapy is one approach that improves adherence, while also providing the antihypertensive efficacy needed to help patients achieve their blood pressure goals.
W.J. Elliott (Tue,) conducted a review in Elevated Blood Pressure. Single-pill or fixed-dose combination therapy was evaluated. Single-pill or fixed-dose combination therapy improves adherence and provides the antihypertensive efficacy needed to help patients achieve their blood pressure goals.