Six months of exercise training in patients with recent myocardial infarction significantly improved exercise performance without significantly changing rest or exercise ventricular function.
Observational (n=15)
Does 6 months of exercise training improve exercise performance and ventricular function in patients with recent myocardial infarction?
Exercise training after recent myocardial infarction improves exercise performance likely through peripheral adaptations, without significantly altering resting or exercise ventricular function.
We evaluated the effects of 6 months of exercise training (bicycle ergometry, walking and jogging) on exercise performance and ventricular function in patients with recent myocardial infarction. Fifteen patients were selected on the basis of myocardial infarction at least 6 weeks but not more than 6 months before the study and age younger than 65 years. The patients were evaluated by maximal treadmill exercise testing and radionuclide angiography at rest and exercise before and after training. Before exercise training, maximal treadmill exercise time ranged from 1.5 to 11 minutes, ejection fraction at rest from 18% and 67% and end-diastolic volume from 108 to 208 ml. The mean EF was 48 +/- 5% (+/- SD) at rest and did not change at maximal exercise (48.5 +/- 5%). All 11 patients who completed the exercise training program achieved a significant training effect, as defined by a reduction in heart rate at 50% maximal pretraining effort or an increase in maximal treadmill time. The mean ejection fraction and end-diastolic volume and wall motion abnormalities at rest and at comparable pretraining exercise work loads and heart rates were not significantly different after training. Despite a wide range of rest and exercise ventricular function, patients with recent uncomplicated myocardial infarcts significantly increased their exercise performance. Because rest and exercise ventricular function were comparable before and after training, improvement in exercise performance probably resulted from training effects on the peripheral vasculature.
Cobb et al. (Thu,) conducted a observational in Recent myocardial infarction (n=15). Exercise training (bicycle ergometry, walking and jogging) vs. Pretraining baseline was evaluated on Exercise performance and ventricular function. Six months of exercise training in patients with recent myocardial infarction significantly improved exercise performance without significantly changing rest or exercise ventricular function.