Does heart failure treatment guided by BNP levels improve morbidity and mortality in extensively treated patients with chronic heart failure?
BNP-guided treatment does not improve morbidity and mortality in extensively treated chronic heart failure patients, although patients who respond with lowered BNP have better outcomes.
Morbidity and mortality were not improved by HF treatment guided by BNP levels. However, BNP responders had a significantly better clinical outcome than non-responders. Future research is needed to elucidate the responsible pathophysiological mechanisms in this sub-population.
Karlström et al. (Wed,) studied this question.
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