Stimulated-echo acquisition mode (STEAM) MRI significantly improved the blood-infarct signal-difference to noise ratio compared to conventional IR-DHE images (34 vs. 10, P<0.002).
Observational (n=9)
Does composite STEAM black-blood viability imaging improve blood-infarct signal-difference to noise ratio compared to conventional IR-DHE imaging in human subjects?
STEAM MRI provides superior blood-infarct contrast compared to conventional IR-DHE imaging, facilitating more accurate measurement of myocardial infarct size.
Absolute Event Rate: 34% vs 10%
p-value: p=< 0.002
PURPOSE: To develop a breathhold method for black-blood viability imaging of the heart that may facilitate identifying the endocardial border. MATERIALS AND METHODS: Three stimulated-echo acquisition mode (STEAM) images were obtained almost simultaneously during the same acquisition using three different demodulation values. Two of the three images were used to construct a black-blood image of the heart. The third image was a T(1)-weighted viability image that enabled detection of hyperintense infarcted myocardium after contrast agent administration. The three STEAM images were combined into one composite black-blood viability image of the heart. The composite STEAM images were compared to conventional inversion-recovery (IR) delayed hyperenhanced (DHE) images in nine human subjects studied on a 3T MRI scanner. RESULTS: STEAM images showed black-blood characteristics and a significant improvement in the blood-infarct signal-difference to noise ratio (SDNR) when compared to the IR-DHE images (34 +/- 4.1 vs. 10 +/- 2.9, mean +/- standard deviation (SD), P < 0.002). There was sufficient myocardium-infarct SDNR in the STEAM images to accurately delineate infarcted regions. The extracted infarcts demonstrated good agreement with the IR-DHE images. CONCLUSION: The STEAM black-blood property allows for better delineation of the blood-infarct border, which would enhance the fast and accurate measurement of infarct size.
Ibrahim et al. (Thu,) conducted a observational in Myocardial infarction (n=9). Stimulated-echo acquisition mode (STEAM) MRI vs. Conventional inversion-recovery (IR) delayed hyperenhanced (DHE) images was evaluated on Blood-infarct signal-difference to noise ratio (SDNR) (p=< 0.002). Stimulated-echo acquisition mode (STEAM) MRI significantly improved the blood-infarct signal-difference to noise ratio compared to conventional IR-DHE images (34 vs. 10, P<0.002).