Electrophysiological mapping of the coronary sinus and great cardiac vein showed atrial pacing thresholds were lower than ventricular thresholds (P < 0.05), with optimal parameters in the CS.
Cross-Sectional (n=25)
What are the pacing and sensing characteristics of electrodes placed in the proximal cardiac veins in patients with normal sinus rhythm?
It is possible to pace the atrium independent of the ventricle at reasonably low thresholds and detect atrial depolarization without undue cross-talk using closely spaced bipolar electrode pairs in the proximal, middle, and distal CS.
p-value: p=<0.05
The purpose of this study was to develop a better understanding of the pacing and sensing characteristics of electrodes placed in the proximal cardiac veins. A detailed mapping of the coronary sinus (CS) and great cardiac vein (GCV) was done on 25 patients with normal sinus rhythm using a deflectable electrophysiological catheter. Intrinsic bipolar electrograms and atrial and ventricular pacing voltage thresholds were measured. For measurement purposes, the GCV and the CS were each subdivided into distal (D), middle (M), and proximal (P) regions, for a total of six test locations. Within the CS and GCV, the average atrial pacing threshold was always lower (P 5, except for the GCV-D. The average atrial threshold in the CS and GCV ranged from 0.2- to 1.0-V higher than in the atrial appendage. Diaphragmatic pacing was observed in three patients. Atrial signal amplitude was greatest in the CS-M, CS-D, and GCV-P and smaller in the CS-P, GCV-M, and GCV-D. Electrode spacing did not significantly affect P wave amplitude, while narrower electrode spacing attenuated R wave amplitude. The average P:R ratio was highest with 5-mm-spaced electrodes compared to wider spaced pairs. The P:R ratio in the CS was higher (P < 0.05) than in all positions of the GVC. It is possible to pace the atrium independent of the ventricle at reasonably low thresholds and to detect atrial depolarization without undue cross-talk or noise using closely spaced bipolar electrode pairs. The areas of the proximal, middle, and distal CS produced the best combination of pacing and sensing parameters.
Giudici et al. (Mon,) conducted a cross-sectional in Normal sinus rhythm (n=25). Electrophysiological mapping of the coronary sinus and great cardiac vein was evaluated on Intrinsic bipolar electrograms and atrial and ventricular pacing voltage thresholds (p=<0.05). Electrophysiological mapping of the coronary sinus and great cardiac vein showed atrial pacing thresholds were lower than ventricular thresholds (P < 0.05), with optimal parameters in the CS.
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