Titania‐Supported Iridium Subnanoclusters as an Efficient Heterogeneous Catalyst for Direct Synthesis of Quinolines from Nitroarenes and Aliphatic Alcohols

A versatile heterogeneous catalyst consisting of sub-nanosized iridium clusters deposited on titania (Ir/TiO2-NCs) promotes the direct tandem synthesis of quinoline derivatives from readily available nitroarenes and aliphatic alcohols under mild and additive-free conditions (see scheme). The process tolerates the presence of various reactive functional groups and is highly selective.