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Numerous clinical and experimental studies within the past six years have demonstrated that hepatitis, including both the infectious and the homologous serum type, is transmissible to human beings by the parenteral injection of human serum. Apparently the only clinical differentiating characteristic of these two infections, when both are thus transmitted, is the shorter (twenty to forty days) incubation period in the case of the former and the longer (forty to one hundred and sixty days) incubation period in the latter. Neefe 1 has proposed the terminology virus hepatitis I.H. and virus hepatitis S.H. to differentiate the naturally occurring disease from the artificially transmitted homologous serum type. Most commonly reported has been the accidental transmission of hepatitis by means of transfusions of whole blood, plasma and convalescent serum and injections of vaccines to which human serum has been added. 2 Less commonly encountered have been accidental transmission by
Sidney Leibowitz (1949) studied this question.