Crises and Life Changes preceding the Onset or Relapse of Acute Schizophrenia: Clinical Aspects

In a previous publication (Brown and Birley, 1968) we have presented some findings which suggest that life changes and crises frequently precipitate the acute onset, relapse or exacerbation of schizophrenic states. To summarize : consecutively admitted patients diagnosed as suffering from schizophrenia were seen at mental hospitals serving a known catchment area. The first fifty whose onsets occurred within three months of admission and could be accurately dated within a week were included. Both the patient and at least one other informant were interviewed about the occurrence of certain previously defined and datable events occurring to the patient or to close relatives. These included such events as moving house, starting or leaving a job, admission to hospital, birth, marriage or death during the twelve weeks prior to onset. These were classified, according to their apparent independence of the patient's control, as ‘independent’ or ‘possibly independent’. The former were those which could be regarded as outside his control, e.g. discovering a burglary or hearing of a brother's serious illness. ‘Possibly independent’ events were those which were considered to have been within the patient's control but which had not been brought about by any unusual behaviour on the patient's part. They were chiefly changes of job, or of opposite sex friends. (Loss of job would, under certain circumstances, be rated as ‘independent’, e.g. when a whole firm closed down).