Strict versus less restrictive selection criteria identified 7% and 14% of patients with dilated cardiomyopathy as potential candidates for cardiac resynchronization therapy, respectively.
Observational (n=566)
What proportion of patients with dilated cardiomyopathy are candidates for cardiac resynchronization therapy based on strict versus less restrictive criteria?
Only a small minority (7-14%) of patients with dilated cardiomyopathy meet the electrocardiographic and clinical criteria for cardiac resynchronization therapy.
Absolute Event Rate: 7% vs 14%
GRIMM, W., et al .: How Many Patients with Dilated Cardiomyopathy May Potentially Benefit from Cardiac Resynchronization Therapy? The clinical and electrocardiographic Marburg Cardiomyopathy database was analyzed to identify potential candidates for cardiac resynchronization therapy (CRT) with biventricular or left ventricular pacing among 566 patients with dilated cardiomyopathy (DCM). All of the following restrictive selection criteria were fulfilled by 38 patients (7%): NYHA functional class ≥ 3 ( n = 193 , 34%), left ventricular ejection fraction (LVEF) <30% (n = 238, 42%), sinus rhythm ( n = 437 , 77%), left bundle branch block (LBBB, n = 142 , 25%), and QRS duration ≥ 150 ms ( n = 136 , 24%). In 78 of the 566 patients (14%) all of the following less restrictive selection criteria were fulfilled: NYHA functional class ≥3 ( n = 193 , 34%), LVEF < 35% in presence of any underlying rhythm (n = 326, 58%), QRS duration ≥ 120 ms with right or left bundle branch block ( n = 223 , 39%). Thus, between 7% and 14% of patients with DCM were candidates for CRT depending on the application of strict versus less restrictive selection criteria.(PACE 2003; 26Pt. II:155–157)
Grimm et al. (Wed,) conducted a observational in Dilated cardiomyopathy (DCM) (n=566). Strict CRT selection criteria vs. Less restrictive CRT selection criteria was evaluated on Eligibility for cardiac resynchronization therapy (CRT). Strict versus less restrictive selection criteria identified 7% and 14% of patients with dilated cardiomyopathy as potential candidates for cardiac resynchronization therapy, respectively.