Does reversible ischemia induced during DSE increase IL-6 and TF plasma levels in patients with coronary artery disease?
Patients with coronary artery disease
Reversible ischemia induced during dobutamine stress echocardiography (DSE)
Interleukin-6 (IL-6) and Tissue Factor (TF) plasma levelssurrogate
Myocardial ischemia induced by stress testing increases inflammatory and prothrombotic biomarkers (IL-6 and TF), which correlate with the severity of left ventricular dysfunction.
Reversible ischemia induced during DSE increases IL-6 and TF plasma levels. IL-6 is related to the extent of left ventricular dysfunction at peak stress and to persistent LV dysfunction during recovery.
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Ignatios Ikonomidis
George Athanassopoulos
John Lekakis
Circulation
National and Kapodistrian University of Athens
Alexandra Hospital
Onassis Cardiac Surgery Center
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Ikonomidis et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69e35154d56a92db71a46de6 — DOI: https://doi.org/10.1161/circulationaha.104.532259