Exercise-related out-of-hospital cardiac arrest was associated with significantly better survival than non-exercise-related arrest (46.2% vs 17.2%; adjusted OR 2.63; 95% CI 1.23-5.54; P=0.01).
Observational (n=2,524)
Does exercise-related out-of-hospital cardiac arrest have a better prognosis than non-exercise-related cardiac arrest?
Exercise-related out-of-hospital cardiac arrest has a low incidence but carries a markedly better prognosis for survival compared to non-exercise-related arrests in individuals over 35 years.
Effect estimate: OR 2.63 (95% CI 1.23-5.54)
Absolute Event Rate: 46.2% vs 17.2%
p-value: p=0.01
AIMS: Although regular physical activity has beneficial cardiovascular effects, exercise can trigger an acute cardiac event. We aimed to determine the incidence and prognosis of exercise-related out-of-hospital cardiac arrest (OHCA) in the general population. METHODS AND RESULTS: We prospectively collected all OHCAs in persons aged 10-90 years from January 2006 to January 2009 in the Dutch province North Holland. The relation between exercise during or within 1 h before OHCA and outcome was analysed using multivariable logistic regression, adjusted for age, gender, location, bystander witness, bystander cardiopulmonary resuscitation (CPR), automated external defibrillator (AED) use, initial rhythm, and Emergency Medical System response time. Of 2524 OHCAs, 143 (5.7%) were exercise related (7 ≤35 years, 93% men). Exercise-related OHCA incidence was 2.1 per 100 000 person-years overall and 0.3 per 100 000 person-years in those ≤35 years. Survival after exercise-related OHCA was distinctly better than after non-exercise related OHCA (46.2 vs. 17.2%) [unadjusted odds ratio (OR) 4.12; 95%CI 2.92-5.82; P 35 years. This study establishes the favourable outcome of exercise-related OHCA and should have direct implications for public health programs to prevent exercise-related sudden death.
Berdowski et al. (Thu,) conducted a observational in Out-of-hospital cardiac arrest (n=2,524). Exercise-related OHCA vs. Non-exercise-related OHCA was evaluated on Survival (OR 2.63, 95% CI 1.23-5.54, p=0.01). Exercise-related out-of-hospital cardiac arrest was associated with significantly better survival than non-exercise-related arrest (46.2% vs 17.2%; adjusted OR 2.63; 95% CI 1.23-5.54; P=0.01).
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