Doppler guidewire assessment can identify microvascular dysfunction in AMI patients with no-reflow by detecting specific coronary flow velocity patterns.
The coronary flow velocity pattern in patients with the no-reflow phenomenon was characterized by the appearance of systolic retrograde flow, diminished systolic antegrade flow, and rapid deceleration of diastolic flow. Thus, the Doppler guidewire allows us to assess the presence of microvascular dysfunction in AMI.
Iwakura et al. (Sun,) studied this question.