Key points are not available for this paper at this time.
Big things come in small packages: MicroRNAs (miRNAs) are small regulatory RNA molecules in eukaryotes. Altered miRNA expression patterns can be used as a diagnostic tool, for example, in patients with chronic lymphatic leukemia. Also, the inhibition of miRNA function in vivo has been recently achieved by using “antagomirs”—antisense cholesterol conjugates (see scheme; miRNP=miRNA–protein complex, RISC=RNA-induced silencing complex).
Christoph Arenz (Fri,) studied this question.