Method Development and Validation of Metformin Hydrochloride in Tablet Dosage Form

A simple, reproducible and efficient method for the determination of metformin hydrochloride (MET) was developed and validated. The analysis complied with Beer′s law in the concentration range of 8‐13 μg/mL at 233 nm for MET. In our study the validation of analytical method for determination of MET by UV in tablets formulation was performed in accordance the parameters including‐system suitability, specificity, limit of quantification, limit of detection, linearity of response, accuracy, precision (reproducibility & repeatability), robustness (change of wave length±2 nm).