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We show that SirT1 regulation of antioxidant genes in vascular endothelial cells depends on the formation of a FoxO3a/PGC-1α complex.
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Yolanda Olmos
Francisco J. Sánchez-Gómez
Brigitte Wild
Antioxidants and Redox Signaling
Universidad Autónoma de Madrid
Centro de Biología Molecular Severo Ochoa
Spanish National Centre for Cardiovascular Research
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Olmos et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69dd4ae7caee84831440c491 — DOI: https://doi.org/10.1089/ars.2012.4713